Panthers QB Sam Darnold threw for just 120 yards against Seattle last week, and the Panthers still scored 30 points as they ran for 223 yards. The Seahawks in recent weeks have looked like a defense incapable of stopping anyone. But Purdy is questionable for this game with an oblique injury, and the Niners will be without Deebo Samuel. The 49ers are coming off of a dominant 35-7 win over the Bucs, in which Brock Purdy looked more than capable of steering the ship and Christian McCaffrey totaled 153 yards from scrimmage. Season record: 109-93-6 San Francisco 49ers at Seattle Seahawks (+3) Stats are from TruMedia/Pro Football Focus unless otherwise noted. Lines are from FanDuel as of Wednesday night. Week 15 features an NFC West showdown on Thursday night between the Seahawks and 49ers, three Saturday games, and a Sunday nighter between Daniel Jones and Taylor Heinicke.
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